Sentence examples for potent transition from inspiring English sources

Inhibition of MTAP's enzymatic activity with a potent transition state inhibitor failed to significantly reverse any of the functional effects of MTAP expression, despite effectively inhibiting MTAP's enzyme activity in cell extracts and causing the accumulation of MTA.

This article presents two case studies of patients diagnosed with T-cell acute lymphoblastic leukemia who relapsed following allogeneic hematopoietic stem cell transplantation and were subsequently enrolled in a clinical trial in which they received forodesine hydrochloride, a rationally designed, potent, transition-state inhibitor of purine nucleoside phosphorylase.

Wu et al. [14] showed that the pyridoxyl-histidine methyl ester (PHME) acts as a potent transition-state inhibitor of histidine decarboxylase (hHDC) in human cells.

Salophenes display potent binding with transition metal elements and are closely related to salens containing Schiff's bases that are constituted of aliphatic diamines.

Through this process of model based hypotheses generation and testing, the degradation rates of Hes1 and Mash1 mRNA and the dissociation constant of Mash1-E47 heterodimers are identified as the most potent mediators of the transition towards neural differentiation.

FLC is a potent inhibitor of the transition to flowering integrating the autonomous and the vernalisation pathway [ 62].

This is consistent with the fact that the expression level of Cln2 is about three times higher than Cln1 and with the previous finding that Cln2 is more potent in the Start transition (Huh et al., 2003; Tyers and Futcher, 1993; Tyers et al., 1993).

Because microRNAs are capable of re-arranging the molecular landscape in a cell-type-specific manner, we argue that alterations in miR-128 levels are a potent mechanism of bidirectional transitions between GBM subpopulations, resulting in intermediate hybrid stages and emphasizing highly intricate intra-tumoral networking.

His predecessor, Jiang Zemin, had refused to surrender this last, and arguably most potent, of titles when the transition to Mr Hu began in 2002.

The E-box-binding transcription factor, Snail1, functions as a potent inducer of the mesenchymal transition and invasive phenotype of epithelial cells.

As a prominent profibrotic cytokine and potent inducer of epithelial mesenchymal transition (EMT), TGF-β contributes to these processes in liver epithelial cells.