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In view of the current demand of amylases in various industries, the amylase from strain ALA4 could be a potent substitute of chemical processes involved in starch hydrolysis.
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The Ministry of Health has advised hospitals to prepare for a surge in people seeking help after being forced to quit the potent dope substitutes cold turkey.
The most potent compound 18e, substituted with benzamide at this position, displayed minimum inhibitory concentrations (MICs) of 0.27 μg/mL against Mtb H37Ra and 1.36 μg/mL against S. aureus.
A potent series of substituted (2S,4S -benzylproline α2S,4S -benzylproline designed from the readily available starting material (2S,4R)-hydroxy-l-proline. The ligands have improved pharmacokinetic profile over the (4S)-phenoxyproline derivatives described previously and have potential for development as oral agents for the treatment of neuropathic pain.
These histomorphometric results suggest that the fabricated graft can function as a potent osteoconductive bone tissue substitute.
Most of N6-substituted-4′-thioadenosines were less potent in binding than the corresponding N6-substituted-adenosines or N6-substituted-4′-thioadenosine-5′-uronamides.
Furthermore, it was also found that the N-alkyl substituted derivatives were more potent than the N-aryl and N-benzyl substituted compounds against most cell lines.
Recently, we reported on bicyclic substituted hydroxyphenylmethanones as potent inhibitors of 17β-HSD1.
It was found that methoxy and hydroxyl substituted chalconesemicarbazones exhibited potent reducing power and unsubstituted compound showed less reducing potential.
Green porous and ecofriendly scaffolds have been considered as one of the potent candidates for tissue engineering substitutes.
The results provided a practical tool for guiding the design and synthesis of novel and more potent tetronic acid derivatives containing substituted phenylhydrazine moiety.
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