Exact(7)
ESRD may create a potent stress and stimulus for pica, especially in those patients with an underlying cultural predisposition [ 1].
Cortisol is a potent stress hormone and the secretion is regulated by the Hypothalamic-Pituitary-Adrenal-axis (HPA-axis).
We further show that JNK is stimulated to phosphorylate YAP upon UV irradiation, one of the most potent stress activators of the JNK pathway.
Although a mild stress induces a protective response, a more potent stress stimulus induces apoptosis, and an even stronger one leads to necrosis.
End-stage renal disease (ESRD) may constitute a potent stress and stimulus for pica, which is quite common among dialysis patients [ 1].
Quite the contrary, our data suggest that some substances used in ILD therapy, especially azathioprine, pose potent stress factors per se.
Similar(53)
As previously shown, MGO constitutes a potent stress-inducer by impairing UPS activity, leading to the accumulation of damaged and modified proteins in the cell.
The strong activation of these hypothalamic structures as well as the BNST (the 'stress-reward' interface) raises the possibility that in R mice a more potent "stress-like" neuroendocrine response occurred.
Collectively, these findings suggest that PP2A activation is a downstream target of PKR and the PKR/PP2A signaling axis is required for rapid and potent stress-induced apoptosis.
One of the most potent stresses is randomisation powerfully stirs up feelings of rejection especially in those who already have histories of severe loss or abandonment.
The use of a potent laboratory stress protocol reproducing a job interview (e.g., the Trier Social Stress Test [ 51]) activates the sympathetic adrenomedullary system and the hypothalamic pituitary adrenocortical axis [ 52].
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