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Using structural information from known KDM4 and KDM5 inhibitors, a potent series of pyrazolylpyridines was designed.
A novel, potent series of glucagon receptor antagonists (GRAs) was discovered.
Replacement of the amide led to identification of a potent series of tetralin-amino imidazoles with robust central efficacy.
This novel and potent series of acylides active against antibiotic-resistant respiratory pathogens should be further investigated.
Optimization of this lead afforded a novel potent series of biaryl 1,3,5-trisubstituted benzenes with excellent functional anticoagulant potency.
A novel and potent series of ene-amides featuring azetidines has been developed as FabI inhibitors active against drug resistant Gram-positive pathogens particularly staphylococcal organisms.
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Series 5a e is found to be more potent than series 4a e as depicted in Table 1.
So a potent factual series such as "Blue Planet" was a fairly obvious place to start in delivering a new kind of educational experience.
A potent, selective series of MMP-13 inhibitors has been derived from a weak (3.2 μM) inhibitor that did not bear a zinc chelator.
Or to be more exact, also as Gibson is while he's confessing, I've seen random segments of Simpsons episodes--only segments not because I'm unaware of how potent the series satire can be, but because I just never, as the saying goes, got into it.
In this study, we characterized a more potent second series CD4-specific DARPin 57.2 for macaque reactivity and investigated its activity after a single intravenous injection into rhesus macaques.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com