Due to their capacity to show the unique responses of live cells, microbial cell arrays can serve as a potent analytical route to replace the conventional yet laborious methods currently in use.
Single administration of this Ad vaccine via the intranasal, but not intramuscular, route provided potent immune protection from pulmonary M.tb challenge.
The skin is a potent and important physiologic route of sensitization to diverse allergens (21), whereas mucosal sites are rather regarded as tolerogenic (22, 23).
Overall, the data indicated that systemic and topical applications of VFB to RHE resulted in a common modulation of genes, with the systemic contact being more potent than the topical route.
delivery as a route for generating potent immune response with staggeringly small doses.
When data from all studies were combined (nine experiments using 1185 animals), NESP was determined to be 3.6-fold more potent than rHuEPO for each route of administration when given three times per week.
Cannabis smokers typically adjust their inhalation patterns and smoking topography as a function of cannabis strength (eg, inhaling more forcefully on low potency than high potency cannabis cigarettes; Heishman et al, 1989; Cooper and Haney, 2009), but this titration would be difficult with new routes of very potent THC administration.
In all cases both ZEBOVGP-specific humoral and cell mediated immune responses (CMIR) were generated, although some routes generated more potent humoral responses.
Thus, monoHER provides a potent protective effect against various routes of doxorubicin-induced cell death allowing an efficient protection of heart and endothelial cells reported previously as major targets in doxorubicin-induced cardiotoxicity.
The IM route was the most potent, inducing approximately 2 fold more IFN-γ secreting cells than OR (p<0.001) or IN (p = 0.043) routes.
