Sentence examples for potent rock from inspiring English sources

These results demonstrate that the new 5-isoquinolinesulfonylamides are not only potent ROCK selective compounds, but are also useful compounds for clinical applications.

Treatment with Y27632, a potent ROCK inhibitor, which blocks CME and neurocan-mediated inhibition restored neurite growth to control levels on permissive substrate.

In particular, fasudil hydrochloride, a potent ROCK inhibitor, has been clinically used to treat cerebral vaso-spasm [ 94] and pulmonary hypertension [ 95].

Other potent ROCK inhibitors either interact with the side chain of Asp202 (analogous to GRK2-Ala321) or lack a central ring all together, as is the case with CHEMBL225282.

It's a formula stronger than any of AC/DC's individual members, and one the audience's riotous response shows is still among the most potent in rock music.

Yet his ghost has continued to exert an ever-more potent fascination over rock musicians of all generations.

Finally, three compounds were designed, and biological evaluation demonstrated that these molecular models were effective for guiding the design of potent and selective ROCK inhibitors.

Y-39983, also known as RKI-983, is structurally similar to Y-27632, but 30 times more potent in inhibiting ROCK activity (Tokushige et al., 2007).

It's a less potent form of rocking.

Thus, it stands to reason that if one can develop potent inhibitors of ROCKs that are selective versus most other AGC kinases, then one should be able to develop potent and selective inhibitors of GRKs.

Taken together, our findings suggest that RbFerH acts as a potent iron sequestrator in rock bream and may actively participate in antimicrobial as well as antioxidative defense.