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For these three strategies, the hepatic stage parasites that arise from the immunizing sporozoites clearly provide the most important source of antigens for the induction of the potent protective responses leading to sterile protection.
Thus, monoHER provides a potent protective effect against various routes of doxorubicin-induced cell death allowing an efficient protection of heart and endothelial cells reported previously as major targets in doxorubicin-induced cardiotoxicity.
Lycoricidine derivatives showed potent protective effect.
An in vitro assay showed that most of the resulting compounds had potent protective activity against the oxidative damage.
Our results indicate that curcumin can be potent protective agent against cypermethrin-induced biochemical alterations and oxidative damage in rats.
1a, 1b and their racemates 7, 10 as well as 4c exhibited potent protective activities against hypoxia-induced cellular damage.
Epitope vaccines consisting of immunodominant epitopes and adjuvant molecules enhance the possibility of inciting potent protective immunity.
The aim of mucosal vaccines is to induce broad potent protective immunity by specific neutralizing antibodies at mucosal surfaces and by induction of cellular immunity.
To date, we still lack an ideal strategy for designing envelope glycoprotein (Env) vaccines to elicit potent protective antibodies against HIV-1 infection.
Collectively, these findings indicate that chrysin possesses a potent protective effect against DOX-induced acute cardiotoxicity via suppressing oxidative stress, inflammation and apoptotic tissue damage.
This study clearly shows that flavonoids from C. paliurus exert a potent protective effect against CCl4-induced acute liver injury in mice.
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