Yet in Germany, the opposition Social Democrats, or S.P.D., who will celebrate their 150th anniversary next year, and their left-leaning allies, the Greens, have watched Ms. Merkel peck away at their programs, turning their most potent positions — on nuclear power, the environment, education, child care and wages — into her own.
"Lobbying in New York State is a very low visibility but highly potent political position to be in," he said.
Gemstar has acquired a set of patents for hand-held reading devices and plans to be the exclusive distributor for electronic books using its technology, giving the company a potent central position at the hub between publishers, bookstores and consumers.
With Boston's solid pitching staff, and their potent mix of position players consisting of future Hall of Fame members and established veterans, the team was expected to compete for a second consecutive NL championship.
In February, Mr. Matthews added viewers from the same month in the election year, to 616,000 from 531,000 for his 5 p.m. show, and to 871,000 from 699,000 for the repeat at 7. With the intense interest in the economy and the new president, Mr. Matthews said, "That microphone is more potent than any legislative position".
Analogues with substituents at the ortho or meta position demonstrated potent in vitro antagonistic activity.
Against Gram-negative bacteria, 10a e, which have various alkyl groups containing different numbers of carbon atoms (C0 C3) at the C-7 alkylaminoazetidine position, showed potent and similar antibacterial activities, whereas the activity of 10f (C4, t-Bu) was significantly lower than those of 10a e.
The data provide compelling evidence that our newly synthesized compounds with type B to D hydroxamic acid groups as the zinc binding motif at the N1 position are potent selective inhibitors of HDAC6 and could be investigated preclinically as potential anticancer drugs.
We have successfully synthesized a series of such double lipid prodrugs, with an etherlipid at the sn-1 position and potent drugs like chlorambucil 118 or derivatives of retinoic acid 119, 120 on the sn-2 position.
A molecule incorporating a tetrazole moiety in the P2 position displayed potent inhibition of the N-domain and was 927-fold more selective for the N-domain than the C-domain.
