Sentence examples for potent perk from inspiring English sources
Treatment of cells with GSK2606414, a potent PERK inhibitor, provided a protective effect against IPA toxicity, providing further support for the model that IPA toxicity is mediated by off-target inhibition of PERK.
But now Foxconn, a potent symbol of the perks and perils of globalization, is taking a step that, not all that long ago, would have seemed unthinkable: it is contemplating life far, far beyond Apple.
pERK is a potent driver of cell proliferation and knockdown of cavin-3 initially slowed cell growth; however, proliferation returned to a normal rate after 3 days and exceeded the normal rate after 10 days of knockdown.
Here we explore the potential of targeting two of these arms with new potent small-molecule inhibitors designed against IRE1α and PERK.
Bortezomib, a potent antimyeloma compound, takes advantage of this property and upregulates PERK activity [ 36].
We used thapsigargin, a potent ER stressor that inhibits the ER calcium pump, to activate PERK and induce eIF2α phosphorylation.
With the current configuration of parameters, GADD34 is not potent enough to quickly reactivate translation, but it requires BiP to accumulate and weaken, indirectly though PERK and CHOP, the rate of phosphorylation of eIF2 α.
