Sentence examples for potent pathway from inspiring English sources

Drinking contaminated milk is a particularly potent pathway, but air exposures are also critical.

NAADP signalling plays a major role in reperfusion-induced cell death and represents a potent pathway for protection against reperfusion injury.

Ectopic expression of S100A2 also elucidated that S100A2 regulated PI3K/Akt signaling, a potent pathway involved in epithelial-mesenchymal transition (EMT) [ 24].

Taken together, these results indicate that traditional chemotherapeutic agents are not efficient inducers of necroptosis and that more potent pathway-specific drugs are required to fully harness the power of necroptosis in anti-cancer therapy.

These cells can initiate tumor formation, differentiate along multi-potent pathways and are relatively resistant to conventional chemotherapy [1].

An emerging biomolecular cue is that of RNA interference by which the expression of genes can be silenced through a potent endogenous pathway.

By contrast, tomatidine, an inactive cyclopamine analogue, NS-398 (a COX-2 blocker) and GSI (a potent Notch pathway inhibitor) were without effect.

Gamma secretase inhibitor (GSI) type 1, a potent Notch pathway inhibitor (Sigma, St . Louis MO, USA), was used to examine the potential role of Notch signaling in the smoke-induced malignant transformation.

Data about CAB using a combination of GnRH analogues with newer, more potent AR pathway inhibitors are not yet available.

Thiocoraline is a potent Notch pathway activator and an inhibitor of MTC-TT cell proliferation at low nanomolar concentrations.

Thiocoraline is a potent Notch pathway activator and an inhibitor of medullary thyroid cancer cell line (MTC-TT) cell proliferation at low nanomolar concentrations.