Exact(43)
Indeed, Japan's dwindling, but still potent, lead in technology is a major draw for Asian tourists, who are as likely to visit a Toyota car factory as a Zen temple.
Recent research from the United Nations University on so-called "backyard recycling" at a dump site in Agbogbloshie, Ghana, found potent lead and cadmium contamination in a nearby school and marketplace.
These results rendered 3l a potent lead compound of CHK1 inhibitor for further investigation.
Thus, our findings here would be helpful to discover potent lead compounds for the treatment of cancers.
In this study, we show that the validated derivatives of compound 11 could serve as potent lead compounds for designing novel anti-cancer agents that target microtubules.
Based on the resulted model, an in silico-screening study was also conducted and new potent lead compounds based on new structural patterns were designed for both targets.
Similar(17)
(We can read this from the most potent leads which all have tyrosine moiety).
Here, we report two rosmaricine derivatives might be potent leads which screening from the world largest traditional Chinese medicine database.
FBDD has been used to generate potent leads, pre-clinical candidates, and has led to the development of an FDA approved drug.
These methods are particularly effective at detecting the binding of low affinity, low molecular weight compounds and transforming them into novel potent leads using structure-guided chemistry.
To clarify the essential structure activity relationship for the PARP inhibitors as well as identify potent leads against PARP, a qualitative pharmacophore model were established using a structure-based approach.
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