Sentence examples for potent infectivity from inspiring English sources

Furthermore, these vectors have been shown to be non-toxic and exhibited potent infectivity for proliferating primary HCC cells and HCC cell lines.

DNA vaccines delivered by HPV pseudovirions combine both the safety features of naked DNA and the potent infectivity of viral vector vaccines without the disadvantages associated with each of them.

Macrophage recognition and uptake of HIV-1-infected healthy and dying T cells might take place at all times during natural infection, and both live and dead/dying T cells are potent carriers of infectivity (Sealy et al., 2009).

Structure function analysis of Mov10 suggested that this potent activity on infectivity of HIV-1 is not dependent on its putative RNA-helicase domain.

Thus a possible explanation for potent inhibition of virus infectivity by our peptides could be through the induction of chemokine production, which could potentially inhibit virus attachment and infectivity.

The domain B epitopes elicited mAbs that were potent neutralizers of virus infectivity and blocked hemagglutination; however, they did not block virus mediated cell membrane fusion [ 111].

In this report we demonstrate that iota-carrageenan, a biopolymer derived from red seaweed, is a potent inhibitor of influenza virus infectivity in vitro and in vivo.

Moreover, the rather weak competition of peptides 15D and 15K with chemokines for receptor binding, together with potent inhibition of HIV-1 infectivity, may be therapeutically preferable to high affinity inhibitors of CXCR4 and CCR5, because these peptides would not compromise functions of potentially critical chemokines such as CXCL12 or the CCR5 ligands.

Infected persons progress through a primary stage of infection with high infectivity, an asymptomatic stage with low infectivity, a symptomatic stage with high infectivity, to AIDS death.

From a panel of hydrazonothiazolyl pyrazolinones, we demonstrate that compounds containing naphthyl di- and tri-sulfonic acids inhibit HIV-1 infection in single round infectivity assays with the disulfonic acids being the most potent.

Furthermore, HIV-1 produced by cells expressing Nullbasic had greatly reduced infectivity due to a potent decrease in its ability to undergo reverse transcription.