Sentence examples for potent in generating from inspiring English sources

In our hands, BM-derived CD11+ DCs from C57BL/6 mice transduced with AdhPrP or AdTA, as well as DCs from Tg650 mice transduced with AdTA, were much more potent in generating antibodies to native mPrP than direct immunization with AdhPrP.

Thus to improve the immunization procedure, we inserted human PrP (hPrP) into an adenovirus vector that brings foreign Th specific for capsid proteins and may be potent in generating antibody CD4+ and CD8+ CTL responses against both the viral antigens and the transgene [30].

Biomaterial scaffold based vaccines show significant potential in generating potent antigen-specific immunity.

We assessed the efficacy of DLI and DC in generating potent graft vs neuroblastoma tumour (GVT) reactions following allogeneic BMT.

Compared to controls, all genotypes exhibited a reduction in Amplex Ultrared signals at wound sites, demonstrating the importance of the calcium flash in generating this potent inflammatory signal.

A great deal of effort has been placed in generating more potent and selective derivatives of conventional Pt II) drugs such as cisplatin.

The challenge lies in generating a sufficiently potent response towards them.

However, due to the challenge in generating highly selective and potent PI3Kγ inhibitors, compound effects could be due to off-target activities.

Overall, MT6-MMP was the most potent in cleaving the MBP, BG21 and J37 isoforms and in generating the N-terminal digest product that corresponded to the known 1 15 immunogenic region of MBP.

Hp91 loaded inside PLGA-NPs was significantly more potent in activating DCs, generating nearly a 4-fold increase in HER-2/ neu-specific CTL responses when compared to Hp91 delivered in its free form.

Recombination can be a potent force generating strain-specific variation in microbial populations.