Sentence examples for potent hitting from inspiring English sources

The compound is remarkably potent, hitting its unknown target(s) when applied to cells at a submicromolar concentration.

The most potent hit compound they found exhibited a K i of 5.3 ± 0.3 μM against 3HNR.

Interestingly, when we evaluated the seven potent hit compounds identified in the FdL assay with the SAMDI assay, we found that only one showed inhibition, suggesting that the remaining six compounds are false-positive hits.

Several potent hits were captured.

Compound 12 with IC50 of 2.8 μM is the most potent hit against BACE-1.

Compound 1, the more potent hit, was the subject of further investigation.

Diverse pharmacomodulations induced a shift in the affinity and selectivity profile with final identification of new potent hits.

The most potent hits illustrated IC50 values of 4.2 and 2.60 μM against MDA-MB-231 cancer cell-line.

The identified potent hits with diverse chemical scaffolds may be useful in designing new MMP-13 inhibitors.

These derivatives were then used in high throughput virtual screening simulations (Glide/HTVS) to find potent hit molecules.

The most potent hit, 6a, displayed an EC50 value of 0.87 μM, which is very close to that of quinacrine (0.4 μM).