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With such privileged access to a cornucopia of potent highs, clinicians have a history of becoming addicted to the tools of their trade, although it's always remained a taboo subject.
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The flower provided one of the first medicinal substances known to humanity, as well as a potent high.
Eventually, Mr. Califano added, they do get hooked, and turn to needles to achieve a more potent high.
Methadone's delayed narcotic effect and its lack of a potent high are important reasons the drug can be so dangerous, experts say.
He is by now more drug than cure, promising the potent high of a postseason run while presenting the risk of a very bad and brief trip.
The increase in methadone overdoses and deaths has floored many drug experts because methadone, which does not provide a quick or potent high, has long been considered an unlikely candidate for substance abuse.
Guthrie said that the quasi-legal status of smaller growing arrangements, combined with consumers' preference for potent, high-maintenance weed, has shifted the balance of the pot business away from large-scale farms.
With heroin cheaper than ever, users themselves say, a bag supplying a single potent high averages about $10, or less than the cost of a movie ticket with popcorn.
Houses that sold for $1 million before the crisis have been turned into grow houses, equipped with the high-intensity lights, water and air-filtering systems necessary to produce potent, high-quality marijuana.
This time the news was that the miracle pill had an Achilles' heel, that its time-release matrix could be eliminated completely in a matter of seconds by the simple act of crushing the pill with a spoon, a lighter, even a thumbnail, and that the resulting powder, when snorted or mixed with water and injected, produced a very potent high.
So widely known was Mr. Stanley that he appears in the Encyclopedia Britannica article on LSD under the apparently unironic index term "Augustus Owsley Stanley III (American chemist)." The Oxford English Dictionary contains an entry for the noun "Owsley" as "an extremely potent, high-quality type of LSD".
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