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This active molecule exerts versatile and potent functions primarily through its specific nicotinic and muscarinic receptors (nAChRs and mAChRs, respectively).
This review describes the DC surface landscape, reflects on the different molecules confirmed to be on their surface and how they provide the basis for manipulation and translation of the potent functions of these cells into new diagnostics and immune therapies for the clinic.
The potent functions of FoxO1 are tightly controlled by its transcription and phosphorylation states.
Given the potent functions conferred by Mstn, we surmise that Mstn secretion by cachexia-inducing neoplasms would initiate the pathogenesis of cancer cachexia.
Up to 70 different genes encoding F-box proteins have been identified in the human genome, but only a handful have been characterized (Skaar et al, 2009), some with potent functions as either tumour suppressors or tumour promoters (Frescas & Pagano, 2008; Nakayama & Nakayama, 2006).
Given the potent functions of cyclin D1b on tumor formation described above, it will be essential to define the frequency and distribution of cyclin D1b induction across multiple tumor types, to more completely understand the contribution of this isoform in malignant transformation and tumor progression.
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Mouse CD8+ T cells transduced with an m33-encoding retrovirus showed binding of SIY-Kb and potent function in vitro, but in vivo these T cells disappeared within hours after transfer into syngeneic hosts without causing graft-versus-host disease (GVHD).
These induced (i Tregs are attractive immunotherapeutic agents because of their ease of generation and their potent function in murine models of autoimmunity, but questions remain regarding their stability [10].
Independent of the regulatory mechanisms, our data provide strong evidence for a potent function of the newly discovered AHR-NRF2-SLPI/SPRR2D/EPGN axin in the pathogenesis of MADISH.
miR-210 is recognized to have the potent function of angiogenesis, and in this study intra-articular injection of ds miR-210 could enhance the angiogenesis around the injured site of the meniscus.
Proteins and peptides are excellent therapeutic compounds which have highly specific and potent biological functions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com