This review describes the DC surface landscape, reflects on the different molecules confirmed to be on their surface and how they provide the basis for manipulation and translation of the potent functions of these cells into new diagnostics and immune therapies for the clinic.
miR-210 is recognized to have the potent function of angiogenesis, and in this study intra-articular injection of ds miR-210 could enhance the angiogenesis around the injured site of the meniscus.
Given the potent functions of cyclin D1b on tumor formation described above, it will be essential to define the frequency and distribution of cyclin D1b induction across multiple tumor types, to more completely understand the contribution of this isoform in malignant transformation and tumor progression.
The potent functions of FoxO1 are tightly controlled by its transcription and phosphorylation states.
All the data presented in these studies underline the potent regulatory function of the STN in processing associative and limbic information sent to cortical and subcortical regions.
These induced (i Tregs are attractive immunotherapeutic agents because of their ease of generation and their potent function in murine models of autoimmunity, but questions remain regarding their stability [10].
Direct evidence for the potent signalling and targeting function of the CIN85 binding sites is provided by the ability of the T-cell adaptor SLP76 to respond to BCR activation when equipped with the PXXXPR motifs.
It irreversibly blocks the monocyte-to-DC differentiation, driving the differentiation process toward the macrophage lineage and impair the potent APC function of DC. 53,68,89 Beckebaum et al.
These results revealed the potent promoting function of AEG-1 on Wnt/β-catenin signaling.
In addition, cardiomyocytes were reported to have intrinsically low levels of antioxidant enzymes that may explain the potent protective function of monoHER in these cells (Hrdina et al, 2000).
