Sentence examples for potent feedback from inspiring English sources
However, we also observed that activation of the SNr projection neuron population could elicit a large and potent feedback inhibition capable of shaping output activity.
For instance, we found that the effects of bacterial challenge activating IL-8 gene transcription in epithelial cells, are down regulated by miR-93, which acts as a potent feedback mechanism [ 29].
Nonetheless, we found that potent feedback inhibition could be observed in Gad2-ChR2 mice and that stimulation of GPe axons yielded relatively less inhibition in SNr neurons than either the striatonigral or intranigral pathways under our stimulus conditions.
As described above, the methyl donor substrate SAM is converted to SAH (21), which represents a potent feedback inhibitor of PRMT activity, and accumulates as an inevitable byproduct of protein methylation.
These include (i) allosteric control of anthranilate synthase, whereby Trp acts as a potent feedback inhibitor; and (ii) an attenuator mechanism that is mediated by a Trp-rich leader peptide (encoded by trpL), and repression control mediated by trpR, which binds Trp as a corepressor moiety.
Here, we show that the unique properties of the SNr microcircuit both intrinsic properties of projection neurons and the organization of functional activity combine to implement a potent feedback inhibitory circuit that can exert a divisive gain control effect on the basal ganglia output.
This suggests the existence of a potent regulatory feedback loop between IFNL and IL-28RA.
This could be explained by a potent negative feedback loop triggered by combined Pml and Tsc2 inactivation that impedes further activation of nuclear Akt by loss of Pml.
As the ability to efficiently and inexpensively chill things has grown, so have opportunities to buy chilled things — a potent positive-feedback loop.
For example, in the NPF models, it was possible to obtain accurate sensing but poor polarization amplification, whereas models possessing strong positive feedback produced potent polarization but inaccurate directional sensing under high noise conditions.
Here, informational as well as motivational feedback factors represent potent stimuli for behaviour modification (see [ 19] for a comprehensive review).
