Sentence examples for potent expansion from inspiring English sources
These data indicate that αGC-loaded recombinant CD1d proteins directly trigger the semi-invariant TCR of human iNKT cells, and thus represent a promising tool for rapid and potent expansion of human iNKT cells from patients for subsequent adoptive cell transfer.
It is fair to say that no robust, long-term culture system exists today that is capable of maintaining potent, clonal expansion of adult non-transformed pancreas progenitors over long periods of time under defined conditions.
We find that regardless of baseline Ad5 nAb serostatus, Ad5 vector administration results in a potent restimulation and expansion of pre-existing Ad5-specific CD8+ T-cells.
A series of electron micrographs provided potent evidence for the expansion of ER membranes into mature autophagosomes.
The intent of the present study was to examine the adaptive potential of skeletal muscle mitochondria in old animals in response to a potent stimulus for organelle expansion.
In these experiments, the most potent inhibitor of monolayer expansion was the p44/42 MAPK inhibitor PD098059, while SB203580 failed to block this phenomenon.
TGF-β1 is a potent inhibitor of HSPC expansion (Csaszar et al., 2012; Fortunel et al., 2000) which rapidly accumulates at high levels (>1,000 pg/mL) in this culture system in a manner that mimics the behavior of a number of secreted factors (Fig. 1B).
Particularly striking are the contractions of the T cell repertoire and, through mechanisms likely to involve homeostatic proliferation, clonal expansions of potent effector T cells carrying an unusual phenotype.
Expansion at 5% pO2 also enhanced subsequent osteogenesis of MSCs, whereas differentiation at 5% pO2 was found to be a more potent promoter of chondrogenesis than expansion at 5%pO22.
Selective manipulation of this process might ultimately facilitate expansion of more potent cell populations for regenerative medicine.
We previously reported the establishment of adherent mouse and human neural stem (NS) cell lines that are capable of clonal expansion and tri-potent differentiation [26], [27].
