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Additionally, the most potent compound 14c exhibited good pharmacokinetics properties.
The most potent compound displays IC50 of 3 nM.
The most potent compound 34 displays IC50 of 0.9 nM.
The most potent compound was a carboxypeptidase B inhibitor.
The overall trend showed 4k as the most potent compound.
The most potent compound 9 was as potent as camptothecin.
The most potent compound inhibits ARTD10 with sub-micromolar IC50.
The most potent compound 7l also exhibited topoisomeraseⅡinhibition activity.
The most potent compound causing mitochondrial depolarization was C14G1 followed by 4d.
The most potent compound of each class inhibited the in vitro sumoylation with an IC50 of 11.1 and 13.4 μM.
The most potent compound 36 exhibited improved uncatalyzed stability of GSTπ.
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