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Our results reveal that tanshinone-1 has a potent capability for directly killing MDR tumor cells, independent of drug transporters but partially dependent on reduced Tyr705 phosphorylation of Stat3.
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These effects were potentially achieved by its potent capability to suppress synthesis of pro-inflammatory cytokines such as TNF-α and Fas and ROS.
Consistently with our previous report [15], pCSCs had more potent capability than differentiated TMCs to form a new tumor.
In addition, these cells show a marked downregulation of MHC-II molecules as well as the MHC-II master regulator, CIITA, and combine an impaired capability for antigen presentation with potent phagocytic activity [ 86].
The third is the capability for effective systems integration.
We've definitely got the capability for multi-medal success.
"He has an extraordinary capability for annoying people," said another.
Anyone has the capability for it.
By then ASV (Air-to-surface-vessel) capability for radar homing, all-weather capability and short-take off capability.
Roll on the capability for each action spent boosting a civilisations capability.
For an in vivo anti-tumor assay, the SS-HP/p53 complexes exhibit potent inhibition capability to the growth of tumors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com