However, Masters and Johnson showed that an ejaculate acts as a potent alkaline buffer, which abolishes vaginal acidity within seconds and keeps the vagina neutralized (pH 6 7) for several hours after intercourse [ 38].
The addition of BAPTA-AM, a fast and potent intracellular Ca2+ buffer, however, prevented the induction of autophagy, indicating the importance of cytosolic Ca2+.
Despite its potent activity in incubation buffer, LL-37 was strongly inhibited in the presence of honey.
The representative MUC7 peptide, MUC7 12-mer (RKSYKCLHKRCR), a cationic peptide spanning residues 40 51 of the MUC7, possesses potent antimicrobial activity in low-ionic-strength buffers and in low salt RPMI 1640 medium.
(168) SUMO proteases are very potent and are generally inhibited by employing denaturing buffers.
Alloxan, a potent diabetogenic drug (Sigma, USA), was dissolved in citrate phosphate buffer, pH 7, and injected intraperitoneally at a dose of 75 mg/kg body weight once daily for 10 days to induce experimental diabetes.
When Anastasiades and Akıncı meet in an abandoned, bullet-pocked airport terminal that, like the UN buffer zone which cuts through the island, has become the most potent symbol of its division, there is rare and genuine belief that both will be treading on a path leading to the formation of a federal state.
LPS appeared 10-100-fold more potent than GLA and MPL, while no background responses were observed with the buffer control (AF).
Among these biphenyls, 25 showed potent and selective PPARδ partial agonistic activity (EC50: 5.7 nM), with adequate solubility in phosphate buffer (0.022 mg/mL).
Among the most potent formulations tested, a simple mixture of the vaccine with a microfluidized dispersion of DC-Chol in an aqueous buffer is being considered for further development to produce an improved influenza vaccine.
