Sentence examples for potent at reducing the from inspiring English sources

Acarbose was potent at reducing the PBG level (23.36%) and AUC (31.55%) significantly (P < 0.05).

Importantly, our data indicate that the mutant was potent at reducing the coupling conductance of co-expressed Cx40 and Cx43, suggesting that it exhibits both dominant- and transdominant-negative properties, respectively.

It was noted that CI-1040 was more potent than U0126 at reducing the growth of the C8161 and 1205Lu cell lines.

Therefore, we recommend that highly potent drugs aimed at reducing the need for repeat treatments should be explored for use in wildlife medicine.

Lycopene is a potent anti-oxidant, which has been widely reported for its potential benefits at reducing the risks of certain types of cancer e.g. prostate cancer.

To investigate the contribution of STIM1 in cross-presentation, we knocked down the expression of STIM1 in BM-DCs using four different siRNA, with siRNA #1 and #5 being the most potent at reducing Stim1 mRNA levels without interfering with Stim2 mRNA (Fig. 6a).

After optimization (data not shown) the siRNA oligonucleotide BRAF-C2 which target both wild-type and mutated BRAF was selected, being the most potent at reducing BRAF levels after 48 hours of exposure.

Inhibition of NFκB was most potent at reducing expression of these adhesion molecules (Figure 2d).

Downregulation of NIK was more potent at reducing cell viability than SMG1 silencing in IAP-deficient H226 cells (Supplementary Figures 4B and C).

Although SGC0946 displayed similar potency (IC50 = 0.3 ± 0.1 nM) for DOT1L as EPZ004777 (IC50 = 0.5 ± 0.1 nM) in biochemical assays, it (IC50 = 8.8 ± 1.6 nM) was about 10-fold more potent at reducing H3K79Me2 levels in MCF10A cells than EPZ004777 (IC50 = 84 ± 20 nM) in an in-cell western assay.

When glutamine was at the ATC3 Kact, ATN6 was a potent inhibitor, reducing the AT activity to ∼14% of the uninhibited rate.