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Three compounds showed potent ability to activate both GK and PPARγ.
Compound B7 showed not only the most potent ability to induce thermal stabilization of Hsp90α but also the strongest cytotoxicity.
Most of the compounds exhibited a potent ability to inhibit amyloid-β (Aβ) aggregation and monoamine oxidases.
IL-2, however, has a potent ability to induce the proliferation, differentiation, and activity of a number of immune cells, including T cells.
Cellular thermal shift assay (CETSA) screening showed that compounds B1-13 with (R -Tic scaffold exhibited potent ability to stabilize Hsp90α.
Increasing evidence indicates that T regulatory (Treg) cells have the potent ability to suppress host immune responses, thus preventing autoimmune diseases.
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It has been 10 years since the first report on the antitumor activity of IL-27 against a murine tumor model of colon carcinoma C26, which suggested that IL-27 has potent abilities to induce tumor-specific antitumor activity and protective immunity and that the antitumor activity is mediated mainly through CD8+ T cells, IFN-γ, and T-bet but not through STAT4 [ 24].
These mesenchymal tumor cells have a CD24 -/lo CD44 CD24 -/lo CD44 characteristics of BCSCs, including phenotypemorigenicity, ability to re-establish an epithelial tumor, and enhanced resistance to drugs and radiation [ 60, 61].
Enhancing androgen action through androgen receptor overexpression increased DNL providing further evidence as to the potent ability of this pathway to regulate lipid accumulation.
High expression was also significantly associated with the occurrence of regional recurrence (P=0.025), and poorer OS (P=0.028), perhaps due to the potent ability of VEGF-C to induce both lymphangiogenesis and angiogenesis, thereby providing open channels for dissemination of malignant cells.
The potent ability of AR to enrich the knowledge and visuals of physical content goes beyond marketing purposes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com