Exact(3)
In contrast, its potency was lower than that of docetaxel in MDA-MB-231.
This analogue exhibited a high anti-oxytocic potency (pA2 = 8.22) and moderate pressor antagonism (pA2 = 6.85), while its antidiuretic potency was lower than that of AVP but with a significantly prolonged activity.
The AR antagonistic potency was lower after fractionation, from GPC1 (200 nmol FLU/g dw, to RP3 and RP4 (130 nmol FLU/g dw together) and finally following normal phase fractionation in RP3NP2, RP3NP5, RP3NP6 and RP4NP2 (59 nmol FLU/g dw together; Fig. 5a).
Similar(5)
The synthesized compound 8 showed time-dependent inhibition of GABA-AT, but its potency is lower than that of vigabatrin.
Using recombinant human H2S-producing enzymes we have found that PAG exhibits selectivity towards CSE vs. CBS, but its potency is lower than that of l-aminoethoxyvinylglycine (AVG).
For the induction of the phase 2 cytoprotective enzyme NQO1 in Hepa1c1c7 murine hepatoma cells, the diasteromeric mixture 3a and 3b shows high potency (CD, 75 nM) although this potency is lower than that of 1 and 16.
PAG also exhibits selectivity towards CSE, but its potency is lower than that of AVG.
It has been reported that Mg2+ also inhibits the activity of antimicrobial peptides, but the inhibition potency is lower that that of Ca2+.
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