Sentence examples for potency variations from inspiring English sources

Continuous SAR regions are characterized by the presence of compounds with structural modifications that lead to gradual changes in potency, whereas discontinuous SAR regions contain structural analogs with large (and essentially unpredictable) potency variations.

Regioisomers that showed profound potency variation in previously-reported isoindolinone and aminoindazole systems were surprisingly found to have similar potencies in the case of the indazolinone chemical series.

It is resulted that molecular volume of the amide moiety would be a major factor in inhibitory potency variation of the synthetic amides, where the hydrogen bonding of the amide group could also involve in the activity of the inhibitors.

Although the series of cell sorting experiments indicated that enriching for CD4+CD45RO+ T cells increased the Tck effector potency, variation between different experiments with different donors was very evident.

Notably, the significant potency variation between cell lines and primary T-cell models of HIV-latency emphasize the need to test the HDAC inhibitors in more than one system.

In the current studies, the ovulation-inhibition potency of four variations of this regimen was assessed.

The experiments were performed with a range of RecX concentrations to explore the variation in potency between the mutant and wild-type proteins.

Moreover, the titre values measured by different laboratories were transformed into international units because the use of relative potency reduces the variation between laboratories, in contrast to direct titre estimation [ 15].

Virtually all of these cannabinoids bind to the CB1 receptor in the brain, but beyond that there are enormous variations in potency, functional activity, off-target binding, and an enormously diverse population of users taking different doses often in combination with other drugs.

This difference in potency may reflect the variations in RXR sequence between mammals and parasites.

Large variations in potency are found within the list of compounds that were tested.