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If they don't, or if they lose their potency through compromise and dilution, they aren't.
Structural analyses revealed that the para-substituent improves the potency through hydrophobic interactions with Pro1034 and Phe1035 residues in the binding pocket of TNKS2.
Perhaps that is explanation enough for the seeming clash of aesthetics through the piece but the framing device fails to maintain any potency through the work: Mironov's magnetising performance is enough of an artistic intervention alone.
Vaccine shelf life is best determined utilizing a formal statistical evaluation outlined in the ICH guidelines, while minimum release is calculated to help assure adequate potency through handling and storage of the vaccine.
Of this series of compounds, only compound 31 combined antitumor potency with potent DHFR inhibition; the other active antitumor compounds (19, 41, and 47) all had DHFR IC50 values above 15 μM, suggesting that they might exert their antitumor potency through some other mode of action.
In contrast to utilizing coengagement of antigen with the inhibitory FcγRIIb, there are situations where antigen and FcγR coengagement can dramatically increase mAb potency through avidity-based interactions.
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Exogenous Oct4 improves adult ATSCs cell proliferation and differentiation potencies through epigenetic reprogramming of stemness genes such as Oct4, Nanog, Sox2, and Rex1.
One such ligand is Sonic hedgehog (Shh), whose posttranslational lipid modifications and assembly into multimers enhance its biological potency, potentially through receptor clustering.
The first possibility is that the AMA1-C1 vaccine had lost potency either through degradation over time or because of inadequate transportation or storage conditions.
COX-1 and COX-2 inhibitory potency was evaluated through in vitro cyclooxygenase (COX) assays.
While the F.D.A. questions the legality of drug recycling, it has not received any reports of tainted drugs or drugs that have lost their potency being processed through Aid for AIDS and has not tried to stop its work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com