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We determined the specific potency of the two mAbs with the highest binding affinity against sites 1 and 2, 1269 and 1245, respectively (Feed #1 and #2; Fig. 7a and Supplementary Table 11).
Despite their lack of bacteria-killing effect under a relatively severe experimental setting of dynamic immersion, the biocidal potency of the two Zr-based BMGs was demonstrated via a moist contact assay.
Furthermore, structural damage in fish organs and significant inhibition of AChE in the fish brain suggest the potency of the two biomarkers against pollution.
Although the immune potency of the two viral particles is different, they generate antibodies that recognize the same linear immunodominant neutralization epitope with similar titer (>1/12,800) in the mouse model.
A comparison of the antimutagenic potency of the two protoberberines tested here supports this notion.
These phenomena could be explained by the potency of the two drugs.
Similar(43)
In a rat immortalized granulosa cell bioassay the potency of the three variants towards progesterone secretion varied.
Finally, the rank order of potency of the five NK1 antagonists in the gerbil foot-tapping assay was similar to the potency order in the gerbil elevated plus-maze (Table 2).
The overall estrogenic potency of the three EDCs in mixtures was quantified with an E2 equivalent potency, which was found to distribute well into the solvent at a KE2EQ = 1.43.
Therefore, the potency of the four tested compounds (6AP, 6APi, GA and GAi) to inhibit the assisted folding activity of the ribosome parallels their activity as antiprion drugs.
Hence, the order of potency of the three alleles appears to be: gpd1 L164P > hot1 P107S,H274Y ≥ smp1 R110Q,P269Q.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com