Sentence examples for potency of the existing from inspiring English sources

He argued that such an East-West stoppage would have ended the development of new arms and, more important, reduced confidence in the potency of the existing arsenal.

Whether the hot steak can continue depends on the future strength of the existing films in the market, plus the enduring box-office potency of Mel Gibson.

The emergence of drug-induced mutations of HIV-1 enzymes leads to rapid loss of the potency of existing drugs and the need to develop new candidates [ 11].

In order to accelerate the design of new potent and selective inhibitors targeting dihydrofolate reductase of C. hominis (ChDHFR), we determined the structural basis for the potency of existing DHFR inhibitors using superpositions of the structure of ChDHFR with other species and analysis of active site complexes of ChDHFR bound to ligands exhibiting a wide range of IC50 values.

That makes it all the more important to preserve the potency of existing drugs, he said.

Emergence of these pathogens requires development of novel therapeutic strategies and inhibition of efflux pumps appears to be a promising strategy that could restore the potency of existing antibiotics.

Hence further structural studies are essential to assist drug targeting of Ets TFs in cancer, to increase the scope of Ets surfaces available for inhibition and to increase the potency of existing drugs.

For risk assessment of environmental exposures, use of TEFs may provide an adequate estimate at low doses, given the goal of an order of magnitude accuracy of the current system and the lack of an established database of efficacies similar to the existing database of potencies.

Although challenges abound for the development of new antimitotics, optimization and potency improvement of existing drugs, it is still possible to exploit current drugs under new strategies.

That said, the jury is still out on whether doing this 'showing of the telling' in VR will be any more powerful than the existing potency achieved by other flatscreen-delivered media, be it video, TV or cinema.

The variety in anticancer activity and potency of these compounds suggests potential mechanistic diversity in this set of small molecules, in addition to the existing structural diversity.