Sentence examples for potency in the presence of from inspiring English sources

Stronger germicidal solutions, such as those containing carbolic acid (phenol) or iodine, either damage living cells or lose their potency in the presence of blood serum.

PD 178390 retained antiviral potency in the presence of serum proteins with a modest three-to fivefold drop in antiviral activity in the presence of 40% human serum.

Optimization for several parameters including potency in the presence of human plasma, selectivity against CYP3A4 inhibition and improved rat oral bioavailability led to the identification of 8d which demonstrated antihypertensive efficacy in a transgenic rat model of human hypertension.

As shown in Fig. 3E, we observed a highly significant (p<0.0001) concentration-dependent decrease in choline competitive potency in the presence of T30.

Likewise, OVA and Q4 induced the down-modulation of the OT-I TCR and had a slightly greater potency in the presence of LCKS59A molecules (Fig 7A).

Against W1L2 cells, CB300179 and CB300189 demonstrated reduced potency in the presence of exogenous thymidine (dThd), and against a W1L2 C1 TS overproducing cell line.

Compounds that met acceptable ADME criteria, selectivity, human plasma protein binding, potency shift in the presence of α-glycoprotein were evaluated in rat and dog pharmacokinetics.

The potency of AMCs in the presence of serum translated well to efficacy in the S. aureus MRSA 5 thigh wound infection model.

End-tagging by W/F stretches strongly enhances the bactericidal potency of ultra-short AMPs, even at physiological ionic strength and in the presence of serum.

However, its neoplastic potency was greatly enhanced in the presence of growth factors.

The antifungal potency of a peptide in the presence of cations is of particular importance for evaluation of defense capacity against microorganisms in plants.