Sentence examples for potency in comparison to from inspiring English sources
Among all, compounds having Morpholine, N-methyl/phenyl/benzyl/pyrimidinyl piperazines and n-butylamine substitution at C-7 position, have shown increased potency in comparison to norfloxacin and ciprofloxacin.
Interestingly, 11 exhibited increased potency in comparison to 12 in the HK inhibition assays, perhaps suggesting that the aminobenzothiazole scaffold could be important in the development of HK inhibitors.
As shown in Fig. 5A, hygromycin carrying fUSE5-ZZ-chFRP5 phages inhibited target cell growth by 50%, (Fig. 5A treatment a), a >1000 fold improvement in hygromycin potency (in comparison to the free drug).
Research in homeopathy has traditionally addressed itself to defining the effectiveness of homeopathic potencies in comparison to placebo medication.
This offered a potential opportunity to gain improved potency and selectivity in comparison to compounds such as 1 and 2. Synthesis of a range of analogues with variation of the groups at both R and R was undertaken in order to build the SAR, and examples given in Table 2 illustrate the results from assays against both the PfCDPK1 enzyme and P. falciparum parasite.
20 showed higher potency against TNKS2 in comparison to ortho- and meta-substituted compounds.
The present study reveals the high potency of crude extracts as antioxidants and potential anticancer in comparison to their separated fractions.
The introduction of polarity led to a small loss in potency (20) and the alternative pyridine isomer carrying the isopentylamine substituent (21) displayed a sevenfold loss in potency against the enzyme in comparison to 17.
Relative potency values express the potency of a specific compound in comparison to 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD), the most potent dioxinlike compound, with a relative potency value of 1.
Interestingly, these studies unambiguously demonstrated the greater potency of L-enantiomer in comparison to D-enantiomer.
It also demonstrates a more than 4000-fold greater potency for DPP-4 in comparison to a number of other proteases.
