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A description of this potency can be found in the fourth century Sanskrit dramatist Kalidasa's play "Shakuntala:" First maid.
Heroin is dangerous by dint of the impurities with which it is cut on the black market, and because its potency can be wildly fluctuating, making it easy to overdose.
Optimization of inhibitory potency can be facilitated by structural information about inhibitor target binding.
The development of novel antifungal agents with high susceptibility and increased potency can be achieved by increasing their overall lipophilicity.
Interestingly, the same properties that account for potency can also be exploited to utilize the toxin as a research tool and as a therapeutic agent.
Short antimicrobial peptides are essential to keep us healthy and their lasting potency can inspire the design of new types of antibiotics.
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Therefore, homeopathic products of low dilutions ('low potencies') can contain considerable and sometimes even lethal amounts of harmful substances [43], while high dilutions ('high potencies') might contain only very few or no molecules of the diluted substance.
Given the risk of virus escape mutants, engineering antibodies that target mutationally constrained epitopes with therapeutically relevant potencies can be valuable for combating future outbreaks.
These potencies can be compared to that of casein.
However, this analysis largely considered chemicals for which a mutagenic mode of action has been established and for which a linear, no-threshold dose response function is assumed for the low-dose range being considered for risk assessment, and comparing potencies can be shown to be the same as comparing doses.
Furthermore, based on coarse ranking of compound potency, hits can be followed up by cellular IC50 measurement using NMR spectroscopy, which can also be handled in an automated fashion.
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