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SAR studies showed that in spite of prenyl length increases, the effects of the amide size and its electronic properties on the inhibitory potency became predominant.
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Yet Altman worries that the network's very potency has become problematic.
(Below) There is a continuum of potency that becomes progressively restricted as cells move from a state of 'stemness' to that of terminal differentiation.
It should be clearly stated that, although the suggested structure modifications can be less toxic (as predicted by a QSAR model), they can be unsatisfactory in other respects: they can lose their primary effect (e.g. potency) or become chemically infeasible or unstable.
They're pluripotent, meaning that they have the power, or potency to become many--pluri--different kinds of cells in an organism.
Our results suggest that as cells exit pluripotency they are endowed with a primary neuroectodermal fate and that the potency to become endomesodermal rises with time.
She recalled the battle several years ago when Viagra, the male-potency drug, first became available and some employers and insurers decided not to cover it or to limit payments.
Evaluation of G2 G5 dendrimers in the DNAA series revealed that anti-HSV-2 potency increased as dendrimers became larger, with the G5 dendrimer demonstrating the greatest potency (0.03±0.003 µM) (Figure 1E).
For centuries, sugar had remained out of reach by the lower classes but by 1900 it had lost its symbolic potency and had become a relatively inexpensive commodity.
The potency of Ms. Jones's work became clear in the aftermath of the bombing of a Bali nightclub in October 2002.
By contrast, mutation to produce hFFA2-C4.57G hFFA2-C4.57Geceproducedre although C2 and C3 receptor equipotent, the potency of C5 wherencrealthoughkedly and beC2me significandly (P<0.01) more potent than either C3 oremainedg. 6 D).
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