Interestingly, KatG expression was shown to be 'pulsatile' a feature postulated to be not specific for KatG and probably occurring in many if not all genes and pulses of KatG expression were strongly correlated with ensuing cell death.
Therefore, functional HGF to activate c-Met was reasonably postulated to be secreted from not only CAFs and other inflammatory processes but also tumor cells, although further investigations for clarification is needed.
For the Stress Model mutational stress was not postulated to be the determinant factor a priori but, rather, it was derived from the assumptions of the model that are essentially two (1) there is a single active conformation and (2) mutants are flexible and therefore can sample the active conformation so that they are at least partly functional.
However, it is clear that changes in the membrane fusion activity of the influenza virus HA should not be postulated to explain alterations in overall viral infectivity, since correlation between these two processes may not be linear.
Curcumin, a well-known diarylheptanoid, has been postulated to be of potential use not only in cancer chemo-prevention but also in chemotherapy [ 57].
However, until now, the response to RIT in patients with GD remains unpredictable, and factors postulated to predict the outcomes have not been proved clinically useful or widely adopted in clinical practice.
First, we tested filtration of particles, not the coronavirus postulated to cause SARS.
Thus, conflicting sequence information was postulated not to be due to sequencing errors, but rather due to the high sequence similarity of the HRP isoenzymes and the permissive settings used in the assembly.
Authors postulated not to confound this clinical sign with an aggressive periodontitis.
Whereas mutations of active site residues postulated not to be involved in the catalytic mechanism (Thr48 and Phe252) had no or only minor effects on the kinetic behavior of the enzyme, replacement of Ser47 with alanine or cysteine (thus removing the potential to form the natural hydrogen bonding network) had a significant effect.
