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In the presence of a benzoic anhydride electrophile, the electrocatalytic reduction of O2 occurs by a process postulated to involve a high-valent manganese oxo porphyrin according to a same scheme already described for the metalloporphyrin dissolved in solution.
The neuroadaptations that result in behavioral sensitization in rats have been postulated to involve cocaine-induced changes in neuronal activity that lead to psychostimulant-induced psychosis, as well as pathological craving for cocaine in human addicts (Kalivas et al, 1998; Post and Rose, 1976; Robinson and Berridge, 1993).
BACKGROUND: Induction of apoptosis by tamoxifen has been postulated to involve oxidative stress.
While the detailed mechanism by which UA contributes to intracellular signaling networks is unknown, it has been postulated to involve intracellular redox dependent mechanisms.
Changes associated with tissue ageing and degeneration have been postulated to involve cellular senescence [ 41- 43].
Loss of ΔΨm has been postulated to involve opening of a large permeability transition pore (PTP).
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The key players among enzymes involved or postulated to be involved are desaturases, β-oxidation enzymes, fatty-acyl reductases, and acetyltransferases.
These current dorsal SMG pathways would map closely to the previously identified human dorsal route subdivision involving the inferior parietal lobe, which was postulated to be involved in sensorimotor processing based on semantic object use information, specialised for function-based object-related actions (Binkofski & Buxbaum, 2012).
The AA2-family class II peroxidases require H2O2, and several extracellular enzymes have been postulated to be involved in extracellular H2O2 production.
Such mechanisms are important in the pathophysiology of asthma [ 54, 55], are may be involved in mood disorders [ 56, 57], and are also postulated to be involved in ADHD [ 58].
Since Phenylalanine residues located elsewhere in the protein sequence have been postulated to be involved in ligand binding, Das et al. suggested that these conserved residues might be involved in cytoplasmic substrate recognition [ 59].
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