More precisely, we need to identify among those the functions which would code for the energy-dependent processes we have postulated.
Interestingly the targets identified were postulated to regulate key germ cell migration and proliferation pathways controlled through PDGF and RAC signalling (McIver SC, Roman SD, Nixon B, McLaughlin EA, unpublished observations).
When the first SOD1 mutations were identified they were postulated to give rise to amyotrophic lateral sclerosis through a loss of function mechanism, but experimental data soon showed that the disease arises from a still unknown toxic gain of function, and the possibility that loss of function plays a role in amyotrophic lateral sclerosis pathogenesis was abandoned.
In addition to primary epimutations, a potential indirect genetic abnormality was identified, and both are postulated to be involved in the epigenetic transgenerational inheritance observed.
Schwartz's Value Theory identifies 10 basic values postulated to be universally important in societal functioning [ 2]: power, achievement, hedonism, stimulations, self-direction, universalism, benevolence, tradition, conformity, and security.
Mesosynteny, firstly identified in Dothideomycetes, was recently postulated to be a mode of chromosomal evolution specific to fungi [ 45].
Using cheminformatics, important amino acid residues were identified using information from orthologous Or sequences identifying potential odor-binding regions, which was postulated to be 15 angstroms deep and 6 angstroms wide (Guo and Kim, 2010).
The aim of the present study was to identify terminal sequences of the human bocavirus that were postulated to occur beyond the hitherto published genome sequences [3], [4].
Primary cilia have also been identified in the osteoblast lineage and have been postulated to play a role in osteoblast differentiation [8], [9].
During the past decade, the FDA has identified more than 100 ephedra containing products that have been postulated to be the cause of more than 800 reports of adverse reactions.
