This sharing also allows probing, challenging and comparing techniques for their diagnostic, prognostic and/or theragnostic value, testing new approaches, exploring new avenues and postulating new questions.
ÁK and SG postulated the original research question and revised and re-wrote the paper.
To address this question, we postulated that disease-causing SHP2 mutations affect not only SHP2 phosphatase activity but also its molecular switching mechanism, and thus, detailed comparative analysis of the structure and function of wild-type and mutant SHP2 enzymes will yield insight into the biochemical basis that underlies the pathological processes potentiated by the mutant enzymes.
The following two research questions were postulated to address the research purpose: i) What are the conditions that engage children with mobile apps?
The question we have postulated is well founded since the air pollution is now recognized as one of the most actual problems of human life in many regions, especially in highly industrialized and densely polluted urbanized areas.
In Crown's "House on Pooneil Corners," the Airplane seems to answer the question that they postulated in their closer of one album earlier, the exalted "Won't You Try:" We did try, yet something profoundly larger didn't, or couldn't, and thus, we failed together.
A neurotrophic effect of lithium has been postulated [ 1], and the question raised as to whether lithium exerts great effects in discrete brain regions that have previously been associated with brain atrophy [ 16].
Several hypotheses are postulated since long days to address these questions.
Prior to the work of Freeman, Rubin, and Ford, the existence of such dark matter had been an open question ever since it was first postulated in 1933.
We did not enrol previous users of the service because staff of the Evidence Centre usually facilitate the refinement of clinical questions during consultation sessions and it was postulated that some learning effect would be present.
