Sentence examples for postulated mediators from inspiring English sources

Theoretical basis used in programme design; postulated mediators.

Cancer stem cells (CSCs) may be postulated mediators of the chemoresistance.

The CSCs have been reported to be postulated mediators of chemoresistance, and hence it might be important to comprehend the drug-resistance mechanisms of CSCs to develop a promising therapy to combat chemoresistance.

Similarly abdominal visceral fat appears to be associated with aortic [6] and carotid artery [7] stiffness and with elevated IL-6 and CRP, which have been postulated as mediators [7].

Changes associated with the menopause transition, in particular loss of ovarian function and subsequent decline in endogenous estrogens, have been postulated as mediators of these differences in risk (8, 9).

It is postulated that inflammatory mediators influence cognition via diverse cytokine-mediated interactions between neurons and glial cells.

Amongst the inflammatory mediators postulated to contribute to eosinophil degranulation, eotaxin and/or RANTES have been shown to release CCR3-dependent granule proteins [ 50, 51] in equivalent amounts to PAF, which is considered a potent eosinophil activator [ 52].

BAL fluid from mice exposed to 6 ppm ozone immediately following exposure manifested little inflammation but exhibited AHR; we postulated that a mediator in BAL may induce AHR.

In particular, tumour necrosis factor-α (TNF-α) has been postulated as a mediator in the pathogenesis of interstitial lung disease because of its proinflammatory effects [ 10, 11].

Subclinical inflammation has been postulated as a mediator between air pollution and cardiometabolic risk and has also been linked with impaired glucose metabolism (Kempf et al. 2008; Kolb and Mandrup-Poulsen 2005).

We need mediators, not agitators.