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The most commonly postulated mechanism for the early copeptin elevation in acute illness is that copeptin reflects the activation of the hypothalamus-pituitary-adrenal axis at the hypothalamic level [41].
In pure acetonitrile, confirmation was obtained for the previously postulated mechanism which involved reaction at the anode of electrogenerated halogen with diethyl malonate anions which had been generated at the cathode.
One postulated mechanism for this is the inhibition of extracellular signal-regulated kinase (ERK).
One postulated mechanism of EPC and CPC action is their possible contribution to induction of proangiogenic cytokines (21).
Another postulated mechanism from a study in mice demonstrated that insulin induces megakaryocytes to produce larger platelets [ 28].
Three bisphosphonates, with different structure, antiresorptive potency and postulated mechanism of action, namely pamidronate, zoledronate and clodronate, were analysed.
Another postulated mechanism from a study in mice demonstrated that insulin causes megakaryocytes to produce larger platelets (29).
One postulated mechanism of "cooperativity" suggests that the strongly-bound cross-bridge releases the steric hindrance of tropomyosin to facilitate the attachment of nearby cross-bridges.
One postulated mechanism in the dysregulation of the immune system in systemic lupus erythematosus (SLE) is the aberrant clearance of apoptotic cells.
One postulated mechanism for essential tremor is the over-excitation of glutamatergic olivo-cerebellar climbing fibers, leading to excitotoxic death of Purkinje cells.
One postulated mechanism by which PA and/or weight loss reduces circulating levels of the inflammatory markers is through a decrease in levels of cytokines produced by fat tissue [ 40].
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