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Specifically, MMP-9 may be involved in preterm labor, cervical maturity, and involution of the postpartum uterus.
How shock affects perfusion of the postpartum uterus is not known.
The postpartum uterus is larger and has greater blood flow than the nonpregnant uterus.
Anderson et al. [7] investigated the postpartum uterus removed for postpartum haemorrhage.
Microbial contamination of the postpartum uterus is almost universal during the first week postpartum [9].
Results also show the significant increased expression of GATA2 as involution progresses in the postpartum uterus.
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Conclusions: MMP levels in the pregnant and postpartum rat uterus and cervix are regulated in part by a PGE2-cAMP mechanism.
The postpartum bovine uterus undergoes involution - a process involving uterine size reduction, contraction, caruncle shedding, necrosis and rejuvenation of endometrial tissue.
This study has shown that in the postpartum bovine uterus IGF-I synthesis was localised to sub-epithelial stroma, whilst maximum concentrations of IGF-II and IGF-1R mRNA were in the endometrial stroma and myometrium, respectively.
All cows experience bacterial contamination and tissue injury in the uterus postpartum, instigating a local inflammatory immune response.
Furthermore, during the postpartum period, the uterus undergoes rapid shrinkage with strong contractile activity and endometrium normalization, but little is known about the exact characteristics and regulations of vascular remodelling and regression in the endometrium.
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