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While ROCK is ubiquitously expressed in many tissues and cells in the body, the postnatal expression of Gli2 is primarily restricted to the growth plate [45] and hair follicle [46], [47].
The postnatal expression of the Asxl2 gene trap is highly tissue-specific.
Expression of either Pax3DN or Pax7DN led to decreased levels of Myf5, MyoD and myogenin mRNAs, consistent with the observed effects on MyoD and myogenin proteins, and indicating a requirement for Pax3/7 in postnatal expression of these factors.
The early postnatal expression of CSPG-related structures in the mouse neostriatum described in this study bears some similarities with proteoglycan patterning at corresponding developmental time points described for the caudate/putamen of the rat [44], [45], with some notable differences.
These reports suggest that prenatal exposure to certain immunotoxicants may play a role in postnatal expression of autoimmunity.
In sheep, a single-nucleotide (nt) substitution is associated with altered postnatal expression of GTL2 and DLK1, although their imprinting is not perturbed.
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QPCR was used to precisely investigate the postnatal expression level of GAD related mRNAs in cortex, hippocampus, cerebellum, and olfactory bulb of rats from P1 throughout adulthood.
To determine their expression level and localization in the postnatal rat brain and thus their potential role during postnatal development we, as a first step, investigated the postnatal expression (P1 to P90) of GAD-related mRNAs in cortex, hippocampus, cerebellum, and olfactory bulb (OB) of rats by means of qPCR and their spatiotemporal expression using radioactive in situ hybridization.
It is still controversially discussed also with respect to different species when CR cells in the neocortex reached their peak of postnatal expression, when they begin to disappear from layer 1 and undergo selective cell death by apoptosis or whether they are diluted in the volume of the growing neocortex.
The genes were initially identified by in silico analysis and their transcript characteristics, region-specific expression, postnatal expression, and hormonal regulation, and characteristics of the expressed proteins were characterized in vitro.
Despite its ubiquitous expression and important functions, the postnatal expression profile and subcellular localization of sialin in the salivary gland remains elusive.
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