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Infer the network posterior distribution and the conditional posterior link distributions for regulators in the clusters (here we use MCMC samples from GRENITS).
For the ICN N, we assign the link probability as the maximum of the posterior link probability and the conditional probability (if applicable).
We developed a framework for solving this problem based on the analysis of conditional posterior link probabilities that identifies the interfering sets of regulators.
All these ϕ are in the tail of the posterior link probability distribution (Supplementary Fig. S4a) and significantly larger than the posterior estimate for random links, ρ = 0.0266 ± 0.0010 (distribution standard deviation).
Therefore, causal networks defined by application of a simple threshold criterion, π (γ i j = 1 | D ) > ϕ, are potentially erroneous because interfering regulators may be lost since their posterior link probabilities fall below the threshold ϕ.
Thus, despite similar correlations among the regulators and a similar posterior link probability distribution (Supplementary Fig. S4b) to that in the phosphate depletion experiment, regulator interference, although significant at 35 β-links, was reduced.
Similar(48)
Similary, anterior ablation of the ECM is represented by removing anterior springs, k = 0. To represent the dumpy ov1 mutant, distal links are removed while anterior and posterior links are weakened.
Maguire et al. [61] proposed that the posterior cingulum links incoming information with the activated knowledge representation, hence forming an integrated representation of the discourse.
It is, therefore, suggested that inner speech is produced by frontal regions (BA 44) and it is then transferred via the arcuate fasciculus to posterior regions that link speech production to speech comprehension.
A critical difference between the primate and the human brain is the set of LH structures and white matter connections that link posterior temporal to inferior frontal areas BA 44/45 [Rilling et al., 2008; Rolheiser et al., 2011].
Median Bayesian posterior probabilities for linked and unlinked pairs were 99.8% and 1.0% in env and 99.7% and 0.0% in gag, respectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com