To show that Hsp104 actively untangles proteins, Lindquist and postdoctoral fellow John Glover conducted test tube experiments with tangled clumps of luciferase, the protein that makes firefly tails glow.
Joan Brugge has been an innovator in cancer research since the beginning of her career, when she isolated the viral and cellular forms of the Src protein as a postdoctoral fellow at the University of Colorado.
In 1990, Hall and Rosbash co-wrote a study with one of Rosbash's postdoctoral students, Paul Hardin, demonstrating that the protein encoded by that gene fluctuates over a twenty-four-hour period, rising at night and falling during the day.
She started postdoctoral research at Imperial studying a protein complex in the light-dependent reactions of plants by creating stable mutations in the DNA of bacteria that get energy from photosynthesis.
When Jill Bargonetti was a postdoctoral fellow working on a tumor-suppressing protein, p53, at Columbia University, she was able to publish papers about her work in a leading journal, Cell, and other prestigious publications.
My postdoctoral project used my existing expertise in protein biochemistry and enzyme kinetics, and I also needed to master new techniques, such as cell culture and virology.
I was particularly pleased when we found out that the key enzyme involved in PCNA ubiquitylation is Rad6, the protein I isolated during my postdoctoral studies.
After earning my Ph.D. from New York University with a thesis on control of DNA replication, I went on to postdoctoral training at Columbia University to study how the protein p53 was able to behave as a tumor suppressor.
To look for a possible protein responsible for transporting iron across cell membranes, postdoctoral researcher Hiromi Gunshin and colleagues at Brigham and Women's Hospital in Boston began by feeding rats a low-iron diet.
This training allowed him to discover the p53 protein complexed to SV40 T antigen during his first postdoctoral work at the Imperial Cancer Research Fund ICRFF) labs in London in 1978.
