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The post-escalation presence of 160,000 can't be maintained past next spring unless tours of duty are extended beyond 15 months.
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Although in couple of patients the follow-up was only couple of months post dose escalation as their dose was escalated to higher doses of O-LAR, some patients were followed up to 7 years post dose escalation.
Of these, eight (23%) had a decrease in their median 5-HIAA post dose escalation of at least 10% compared to the pre-escalation level.
We measured the levels of these tumor markers both pre- and post dose escalation in this patient cohort, but found that CGA and 5-HIAA levels after dose escalation were variable, but increased in the majority (70% and 77%, respectively) of patients.
The Lieber Code responded to the rapid, post-emancipation escalation of guerrilla violence in the West and elsewhere.
Symptom frequency was compared pre- and post dose escalation.
The median aggregate pre- and post dose escalation levels was 350 and 360, respectively.
Thirty-five patients had a-HIAA level checked pre- and post dose escalation.
The cohort was followed every 3 months with median duration of follow-up of 2 years post dose escalation.
The median of aggregate pre- and post dose escalation levels was 162 and 197, respectively (Table 2, Figs. 1- 3).
Of the patients who received 40 mg of O-LAR, 33 had radiological assessment pre- and post dose escalation.
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