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In order to correlate changes in expression level of each transcript with changes in the clinical values, we calculated, expression levels and clinical values as (value post – value pre)/value pre, and the mean for all subjects was expressed as percent change.
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* P < 0.05 between pre and post values.
Pre and post values were not significantly different on the parabolic flight day (p = 0.9728).
Post values were determined using the method of Miles et al. [ 15].
Pairwise differences between pre and post values will be calculated using paired t-tests for normally distributed data and Wilcoxon sign rank tests for non-normally distributed data.
The Spearman correlation coefficients were calculated between pre- and post values of all parameters to examine the relationships between the two measurements.
For both reference and test products, log counts from the left and right hands of each subject were averaged separately, for both pre and post values.
After the glove had been taken off, the second post-value was taken (3 h effect).
After the gloves were removed, the second post-value was taken (sustained effect).
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