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The concentration of IL-6 peated at 36 h post Pm infection of mice and remained elevated for the longer period of time (at least to 96 h post infection) [ 22].
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Post-mortem (PM) toxicology aims to detect xenobiotics in autopsy specimens, determine the concentrations of the relevant compounds, and contribute to the interpretation of the findings for cause of death investigations.
We retrospectively identified all patients admitted to our department of Intensive Care during a two-year period (2012-2013) who required CRRT at any time during ICU stay, who died and had post-mortem (PM) examination.
While standard magnetic resonance imaging (MRI) sequences are increasingly employed in post-mortem (PM) examinations, more advanced techniques such as diffusion tensor imaging (DTI) remain unexplored in forensic sciences.
All families had given written consent for research use of tissue and clinical information at the time of post-mortem (PM) examination.
Cases were ascertained by searches of the fetal and perinatal post-mortem (PM) reports generated by a single regional pediatric pathology service over an eleven-year period between 1993 2003.
Non-arthritic post-mortem (PM) cases were used as controls (n = 21).
Therapeutic drug concentrations measured in plasma are of limited value as reference intervals for interpretation in post-mortem (PM) toxicology.
We examined DLB (n = 12) and controls (n = 19) that were matched for age, gender and post-mortem (PM) delay (Table 1, and the MRC UK Brain Banks Network database identifiers are listed in Additional file 1: Table S1).
To determine the specific aetiological cause of death for each case, a standardised post-mortem (PM) examination was conducted, following a standard body system by body system veterinary autopsy routine [ 14] on calves that died or that were euthanized during the follow-up time.
In addition to these five calves (6 ± 3 weeks old), post-mortem (PM) BAL samples were collected and analyzed from three healthy calves (calves D1-3; 13 ± 4 weeks old), to act as controls for BAL samples from BRSV infected animals in study 2. Euthanization was performed by an overdose of general anesthesia (5 mg/kg ketamine and 15 mg/kg pentobarbital sodium) followed by exsanguination.
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