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For these reasons the development of non-invasive, reproducible and validated methods of proliferation measurement will be a major advance for the evaluation of anti-neoplastic agents and for identifying non-responders early in their treatment so that they can be offered alternative and possibly more efficacious therapies.
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Comprehensive meta-analyses stressed the poor quality of many trials [ 16], the heterogeneity among the studies [ 17], and came to different conclusions, ranging from no effect [ 16], or a small effect, with highest-molecular-weight HA possibly being more efficacious than lower-molecular weight HA in treating knee OA [ 17].
Additionally, these new terminals provide a hyperinnervation of striatal cholinergic interneurons but it remains to be determined whether such changes are detrimental, or possibly result in a more efficacious synaptic transmission as postulated by Freund et al. (1984).
While OLT has been used in clinical trials, TBD has been shown to be more efficacious and possibly less toxic than OLT in animals.
Maybe it's more efficacious to turn it around.
Both drugs were more efficacious when treating UTIs, possibly due to the higher bacterial eradication rates.
For example, the price of medication impacts on its efficacy, with more expensive medications being more efficacious than cheaper ones.
It is possible that higher dosages of siRNA may be more efficacious.
It also enables more efficacious antalgic control with respect to systemic analgesia, and possibly a better control of the stress reaction [61].
Our data suggest that Bs20x22 is a more efficacious treatment for NHL than is combination rituximab/HB22.7 and possibly better than the veltuzumab/epratuzumab-based BsAbs.
Possibly more so.
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