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Is it really possible to scale up without becoming the very type of system Jones and the others fled?
Cell lines suitable for stable production of recombinant proteins must be possible to scale up for commercial GMP production.
Scaling up Eccles believes that it is possible to scale up the model but that it probably needs to be used in five or six prisons before real reductions in the prison population are possible.
There are doubts about whether it would be possible to scale up renewable operations to meet the demand necessary for all this hydrogen needed to be mixed with petro-fuel at service stations.
He likens it to the difference between self-checkouts and staffed tills at a supermarket: it may not be quite as convenient, but it's quicker, cheaper, and possible to scale up much more quickly.
Today with better understanding of biochemical engineering aspects, particularly on mathematical modelling and design of bioreactors (fermenters), it is possible to scale up SSF processes and some designs have been developed for commercialisation.
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As long as it is technically and financially possible to scale 'up' by getting capable hardware for running a single, sufficiently large, database backend at the same pace as the load increases, or distributed frameworks that automate distribution can be used, sharding at the application level is not necessary.
Better understanding of biochemical engineering aspects, particularly on mathematical modeling and design of bioreactors (fermenters) has made it possible to scale-up SSF processes and some designs have been developed for commercialization, making the technology economically feasible.
But with budgets in the range of $100 per business in the U.S. and in the "couple of hundreds" for those outside the U.S. you can see how it was imperative that Foursquare roll this out to its wider base as soon as possible to scale it up.
"If we can show through calculations that it is possible to scale it up, the Chinese government plans to build a pilot plant," said Jaffe, who supported his initial research through the University's Project X Fund.
But a billion dollars would probably pose no problem for them.If, of course, it is possible to scale glass accelerators up.
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