Recent advances in fluorescence super resolution microscopy and protein labeling chemistry make possible the visualization and tracking of individual transcription factors as they diffuse and bind to specific targets in the nucleus of living mammalian cells (Mazza et al., 2012; Gavrilov et al., 2013; Izeddin et al., 2014; Chen et al., 2014b).
Future studies may focus on the genetic identification of many possible differentiated cell types and the visualization of their positions in time and space using fluorescent protein reporters.
Computers now allow microsecond timescale molecular-dynamics simulations, which make the visualization of such processes possible.
To make the visualization of PCR products possible in real time, a SYBR Green I supermix (Yeastern Biotech Co., Taipei, Taiwan) was used.
At first release, we did not include the PI family or their bioactive PIPx metabolites given the significant challenges associated with automating the visualization of all theoretically possible combinations of sn-1 and sn-2 carbon chain lengths, linkages, and variations in phosphorylation of the phosphoinositol head group.
Integration of adaptive optics (AO) into ocular imaging systems has made the visualization of living human photoreceptors possible [ 1– 14].
The visualization of degenerative joint pathologies is possible by radiography [ 15] and MRI [ 16, 17].
Furthermore, through the visualization of bright field images it was possible to discern a columnar structure.
Dr. Bill Kowalik, a scientist at the Chevron Petroleum Technology Company in San Ramon, Calif., who specializes in the visualization of data, has examined the core technology and pointed to possible practical applications.
