Sentence examples for possible that the perturbation of from inspiring English sources

Thus, it is possible that the perturbation of signalling pathways in the prostate is mediated by protein modifications that occur in the extracellular environment.

It is possible that the perturbation of MAP9 homeostasy may participate in the phenotype of cancer cells and that its expression in these cells is still sufficient to allow mitosis to proceed, or that other pathways may overcome MAP9 deficiency.

Given these observations, it is possible that the reported perturbation of mitochondrial transport associated with Alzheimer's disease is caused by an elevated level of HDAC6 and a consequent alteration of the cellular trafficking machinery.

Fig. 2 The two possible situations after the perturbation of the clusters centers.

It is also possible that the perturbations cause an increase in noisy gene expression.

Briefly, it would be possible that a perturbation of FOXL2 expression through somatic hypermethylation, locus heterozygous deletion or regulatory mutations (i.e. in enhancer sequences, promoter, UTRs,.) could play a role in malignant transformation, in a context where no mutations in the coding region are detected.

It is possible that the net effect of perturbation of these pathways may reduce the risk of cell proliferation, and maintain cell and tissue homoeostasis.

Since TCR engagement induces rapid changes in cytoskeletal reorganization in T cells, which is critical for transducing signals, it is possible that perturbation of the actin cytoskeletal reorganization processes in Pak2-deficient thymocytes prevents normal TCR-mediated signaling events.

However, other mechanisms of bringing PDK1 and PKB into proximity, for example involving scaffolding proteins have been described [ 46]; so it is also possible that perturbation of the membrane proximal cytoskeleton via suppression of Slk and Lok activation might be responsible for D1870′s effects.

A second possible mechanism is related with the perturbation of protein stability.

Adenosine closed KCa3.1 following IgE-dependent activation, but it was possible that this effect might occur indirectly through the perturbation of complex intracellular signalling pathways.